IntJOphthalmol。Vo1.9.No.12.Dec.2009www.IJO.cnTel:029-8224517283085628Email:IJO.2000@163.com·实验论著·益视汤对脾气虚证兔视网膜脱离复位后视网膜组织形态的影响张妍春,王卉芳,杨新光,朱赛林,毕春潮,李亚芙。基金项目:中国西安市科技计划资助项目(No.GG05138)作者单位:(710004)中国陕西省西安市第四医院眼科;病理科;检验科;(710014)中国陕两省西安市,西安古城眼科医院作者简介:张妍春,硕十,主治医帅。通讯作者:张妍春.zhangyanchunl239@sohu.eom收稿口期:2009—11—25修回日期:2009一l2—07Afectionofthechineseherbaldrugdecoc-tionofyishionthespleen-qideficiencymodelsrec0nstructi0n0freattachedretinaYan.ChunZhang,Hui—FangWang,Xin-GuangYang.Sai.LinZhu.Chun-ChaoBi,Ya-FuLiFoundationitem:ScienceandTechnologyProjeetXi’a13,China(No.GG05138)DepartmentofOphthalmolog,y;!DepartmentofPathology;Clinicallaboratory.theFourthHospitalofXi’all,Xi’an710004,ShaanxiProvince,China:Xi’anGuchengEyeHospital,Xi’an710014,ShaanxiProvince,ChinaCorrespondenceto:Yan—ChunZhang.DepartmentofOphthahnology,theFourthHospitalofXi’an.Xi’an710004,ShaanxiProvince.China.zhar】gvan(hun1239@sohu.coinReceived:2009—11—25Accepted:2009—12—07Abstract·AIM.ToobservetheafectionofthechineseherbaIdrugdecoctionofyishionthespleen—qideficiencymodelsreconstructionofreattachedretina.·METHODS:Twenty—sixhealthypigmentrabbitswererandomlydividedintoexperimentalgroupsandcontrolgroup.Thespleen—qideficiencymodelswereinducedbyexhaustingandbreakingthespleen—qiwithpotentChineseherbaldrugsandstarvingandsatisfyingtherabbitsabnormaI.ThentherabbitseyeswereoperatedtoproducethemodeIofretinaldetachmentbyinfusionofsodiumhyaluronatebetweentheneurosensoryretinaandthepigmentepithelium.ObservethehistomorphologyofreaRachedretinaafter10,20,30p0stOperativedays.·RESULTS:TherewereseriouspathologicchangesandaslowrecoveryontheretinaIcellsofdeficiencyofspleen—qigroup.Theexperimentalgroupwithchineseherbaldrugdecoctionofyishihadanobviousimprovementoftheseriouspathologicchanges。·CONCLUSION:ThechineseherbaIdrugdecoctionofyishicanrelievethenegativeeffectsonthereattachedretinathatthepathologyofdeficiencyofspleen—qisyndromebrings.andthecurativee仟ecthasrelationwithadministrationtime.·KEYWORDS:thechineseherbaldrugdecoctionofyishi:thepathologicalstateofdeficiencyofspleen—qi;retinaldetachment;thehistomorphologyofreattachedretinaZhangYC,WangHF,YangXG,eta/.Affectionofthechineseherbaldrugdecoctionofyishionthespleen—qideficiencymodels’reeon—structionofreattaehedretina./ntJOphthalmol(GuojiYankeZazhi2009;9(12):2295—2297摘要目的:观察中药益视汤对脾气虚证兔视网膜脱离(retinaldetachment,RD)自动复位后视网膜组织结构恢复的影响。方法:将健康成年新西兰灰兔26只随机分为脾气虚型RD自动复位组(A组)、益视汤治疗组(B组)及空白对照组(C组),采用耗气破气加饥饱失常法建立脾气虚证动物模型,在显傲镜下行视网膜下注射透明质酸钠术建立视网膜脱离自动复位动物模型,用光学显微镜分别观察比较术后10,20,30d视网膜组织结构的变化。结果:B组较A组兔视网膜组织结构紊乱明显改善,细胞水肿变性明显减轻。结论:益视汤能减轻脾气虚证对视网膜脱离自动复位后各层组织细胞的不良影响。关键词:益视汤;脾气虚证;视网膜脱离;视网膜组织形态DOI:10.3969/i.issn.1672-5123.2009.12.011张妍春,王卉芳,杨新光,等.益视汤对脾气虚证兔视网膜脱离复位后视网膜组织形态的影响.国际眼科杂志20O9;9(12):2295-22970弓l言前面的动物实验结果已经表明脾气虚证对视网膜...