CD21CD35CD23S-100CD34CD31S-100LCAcytokeratinsdesminEMACD45D2-40CD68CD1aKi-67CD56CD4CD11cCD14CD20vimentinLysozyme,podoplanin,claudinclusterin(丛生蛋白)HLA-DRThecellswereimmunopsitiveforCD21,CD35,CD23,S-100,CD34,CD31,S-100;Leucocytecommonantigen,andHumanleukocyteantigen-DRwerealsopositiveinsomecells.CD4CD11cCD14CD45CD68HLA-DREMACD21,CD45,leukocytecommonantigen,S100,CD23,CD35,CD1a,desmin,andcytokeratins.ThetumourcellsshowedpositiveimmunohistochemicalstainingforCD23andvimentin(波形蛋白),andnegativestainingforcytokeratin,LCA,S100,CD31,CD34,HMB-45anddesmin.结蛋白滤泡树突状细胞肿瘤/肉瘤流行病学在英文文献中仅有56例被证实,其中24例发生在淋巴结外,包括:肝、腹膜、胰腺周围区域、扁桃体、硬腭、喉、甲状腺、肺、软组织和乳腺。组织病理学其特征与肿瘤侵袭进展相关,包括凝固性坏死、核不典型性及核分裂相>5/10HPF。免疫组化:百分比根据文献总结得出。CD2195%CD3595%神经生长因子受体90%EMA1/1CD1a0/1CD30/1CD200/1CD45(LCA)0/1CD68(KP-1)0/1S-1000/1HMB-450/1Bcl-20/1Cam5.20/1AE1/30/1SMA0/1Desmin(D33)0/1vimentin0/1鉴别诊断1、纤维母细胞性网状细胞肉瘤:表达desmin,SMA和cytokeratins。2、交错(指)突网状细胞肉瘤:表达CD45RB、S-100和CD1a。3、炎性假瘤预后低度恶性肉瘤大约有一半病例复发,25%发生转移。45例中有7例死于肉瘤。