摘要实验以产品的不同点和GMP的相关要求，从实际情况出发，对产品生产工艺做出合理的分析和演示。生产设计的步骤主要是以下几点（1）生产设计。根据《中国药典》2012年版三拗片的车间生产工艺和生产方法，计算并画出生产工艺流程图。（2）反应料计算。（2）根据生产任务及生产制度确定批量为200万片，在200万片批量的基础上完成各工序的物料衡算。（3）设备选型。利用各个生产步骤的物料投入含量和产率，根据各个基本操作各类型的生产范围，选出设备的最佳型号，合理的安排生产工作人员进行周期性工作。（4）车间设置。保证生产条件合理，生产安全以及环境保护良好的原则下，按照分类和就近原则，对车间的整体布局进行设计，达到车间设计的最佳效果。（5）非工艺设计。根据《建筑设计防火规范》等其他的规范和生活标准，从废物处理、安全防火以及劳动安全等多方面对非工艺进行处理。关键词：三拗片；GMP；车间设计；工艺设计AbstractBasedonthedifferencesofproductsandtherequirementsofGMP,thispapermakesareasonableanalysisanddemonstrationoftheproductionprocessfromtheactualsituation.Thestepsofproductiondesignaremainlyasfollows(1)productiondesign.Accordingtotheworkshopproductionprocessandproductionmethodofthe2012editionofChinesepharmacopoeia,theflowchartofproductionprocessiscalculatedanddrawn.(2)calculationofreactionmaterial.(2)accordingtotheproductiontaskandproductionsystem,thebatchof2millionpiecesisdetermined,andthematerialbalanceofeachprocessiscompletedonthebasisof2millionpiecesofbatch.(3)equipmentselection.Usingeachstepofproductionmaterialinputcontentandyield,accordingtothebasicoperationofvarioustypesofproductionrange,choosethebesttypeoftheequipment,thearrangementofthereasonableproductionstaffworkperiodically.(4)workshopsetting.Ensurereasonableproductionconditions,productionsafetyandenvironmentalprotectionundertheprinciplesofgood,inaccordancewiththeprincipleofclassificationandnearby,theoveralllayoutofworkshopdesign,toachievethedesiredeffectoftheworkshopdesign.(5)non-technologicaldesign.Accordingtootherstandardsandstandardofliving,suchas"buildingdesignfirepreventioncode",wecandealwiththenon-processfromwastedisposal,safetyfirepreventionandlaborsafety.Keywords:Infantilestagnationspleenpill;GMP;Workshopdesign;Processdesign目录1绪论..........................................................................................................................11.1设计的背景及目的和意义..........................................................................................11.1.1设计的背景..............................................................................................................11.1.2设计的目的和意义..................................................................................................11.2设计的研究现状.........................................................................................................21.3工艺设计思路..............................................................................................................32工艺流程及物料衡算..............................................................................................42.1产品信息......................................................................................................................42.2标准处方及工艺流程图.............................................................................................42.3物料衡算.....................................................................................................................62.3.1工业配方...
